PROTAC SMARCA2/4-degrader-11
Product Specifications
CAS Number
2568276-71-9
Bioactivity
SMARCA2 degrader-1 (compound I-321) is a PROTAC degrader with a DC50 for SMARCA of less than 100nM, featuring a structure that incorporates a SMARCA inhibitor, a linker, and an E3 ligase ligand.
Smiles
O=C1NC(=O)C(N2C(=O)N(C=3C2=CC=CC3C4CCC(N5CCC(N6N=CC(=C6)C=7C=C(N=NC7N)C=8C=CC=CC8O)CC5)CC4)C)CC1
Molecular Formula
C37H41N9O4
Molecular Weight
675.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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