AZ683
Product Specifications
CAS Number
953798-95-3
Bioactivity
AZ683 is an effective selective inhibitor of the 3-amino-4-anilinoquinoline CSF1R, demonstrating a high affinity for CSF1R (Ki=8 nM; IC50=6 nM) . It also possesses favorable oral bioavailability. [11C]AZ683 can be used as a positron emission tomography (PET) tracer for the colony stimulating factor 1 receptor (CSF1R) .
Smiles
O=C(N)C1=CN=C2C=C(OCC)C(=CC2=C1NC3=CC=C(F)C=C3F)N4CCN(C)CC4
Molecular Formula
C23H25F2N5O2
Molecular Weight
441.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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