(S) -OTS514
Product Specifications
CAS Number
1338541-25-5
Bioactivity
(S) -OTS514, the S-enantiomer of OTS514, is a potent inhibitor of TOPK with an IC50 of 2.6 nM. It effectively inhibits the growth of TOPK-positive tumor cells and induces cell cycle arrest and apoptosis.
Smiles
OC=1C(=C2C3=C(C(=O)NC2=C(C)C1)SC=C3)C4=CC=C([C@@H](CN)C)C=C4
Molecular Formula
C21H20N2O2S
Molecular Weight
364.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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