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(S) -OTS514

Product Specifications

CAS Number

1338541-25-5

Bioactivity

(S) -OTS514, the S-enantiomer of OTS514, is a potent inhibitor of TOPK with an IC50 of 2.6 nM. It effectively inhibits the growth of TOPK-positive tumor cells and induces cell cycle arrest and apoptosis.

Smiles

OC=1C(=C2C3=C(C(=O)NC2=C(C)C1)SC=C3)C4=CC=C([C@@H](CN)C)C=C4

Molecular Formula

C21H20N2O2S

Molecular Weight

364.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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