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KRAS inhibitor-24

Product Specifications

CAS Number

3030576-47-4

Target

Kras, Ras

Related Pathways

MAPK

Bioactivity

KRAS inhibitor-24 (compound 115c), a pyrido-pyridine class KRAS inhibitor, exhibits potent activity against KRas G12V, KRas WT, and KRas G12R, with IC50 values all below 100 nM.

Smiles

C(OC1=NC2=C3C(=N1)C(F)=C(N=C3)C=4C(=C(Cl)C=C(O)C4)CCCCC(=O)NCC[C@]5(CN2CCC5)[H])[C@@]67N(C[C@H](F)C6)CCC7

Molecular Formula

C33H39ClF2N6O3

Molecular Weight

641.15

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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