KRAS inhibitor-24
Product Specifications
CAS Number
3030576-47-4
Target
Kras, Ras
Related Pathways
MAPK
Bioactivity
KRAS inhibitor-24 (compound 115c), a pyrido-pyridine class KRAS inhibitor, exhibits potent activity against KRas G12V, KRas WT, and KRas G12R, with IC50 values all below 100 nM.
Smiles
C(OC1=NC2=C3C(=N1)C(F)=C(N=C3)C=4C(=C(Cl)C=C(O)C4)CCCCC(=O)NCC[C@]5(CN2CCC5)[H])[C@@]67N(C[C@H](F)C6)CCC7
Molecular Formula
C33H39ClF2N6O3
Molecular Weight
641.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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