BVB808
Product Specifications
CAS Number
1414587-22-6
Bioactivity
BVB808 (NVP_BVB808) is a selective inhibitor of JAK2, exhibiting approximately 10 times greater selectivity for JAK2 compared to other members of the JAK family (such as JAK1, JAK3, or TYK2) in vitro. By inhibiting the activation of JAK2, BVB808 reduces the phosphorylation of STAT5, thereby blocking the cell proliferation and survival signaling pathways that depend on JAK2. This compound is utilized in cancer research.
Smiles
N(C=1N=C2N(C=CC2=CN1)C3=CC(F)=C(CN4CCOCC4)C(F)=C3)C5=CC=C(C=C5)N6C[C@@H](C)N[C@@H](C)C6
Molecular Formula
C29H33F2N7O
Molecular Weight
533.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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