BML-260
Product Specifications
CAS Number
101439-76-3
Bioactivity
BML-260 is a potent dual-specificity inhibitor of the phosphatases JSP-1 and DUSP22. It can activate UCP1 and induce thermogenesis in adipocytes independently of JSP-1. The effects of BML-260 on adipocytes partially occur through the activation of the CREB, STAT3, and PPAR signaling pathways. This compound is useful for research on inflammation, proliferative disorders associated with JNK signaling dysfunction, and obesity.
Smiles
O=C(O)C1=CC=C(C=C1)N2C(=S)SC(=CC=3C=CC=CC3)C2=O
Molecular Formula
C17H11NO3S2
Molecular Weight
341.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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