SHetA2
Product Specifications
CAS Number
361483-66-1
Bioactivity
SHetA2, a heterocyclic retinoid derivative, exhibits cytotoxic properties against cancer cells with an IC50 range of 0.37–4.6 μM. It promotes differentiation in cancer cells and induces cell apoptosis (apoptosis) via the mitochondrial intrinsic pathway, while arresting the cell cycle at the G2 phase. SHetA2 also demonstrates antitumor activity and favorable pharmacokinetic properties in mice, with oral activity.
Smiles
O=N(=O)C1=CC=C(C=C1)NC(=S)NC2=CC=C3SC(C)(C)CC(C3=C2)(C)C
Molecular Formula
C20H23N3O2S2
Molecular Weight
401.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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