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UNC10245380

Product Specifications

Target

TNF, Akt, ERK

Related Pathways

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis, MAPK

Bioactivity

UNC10245380 is a CIB1 inhibitor with an IC50 of 8 μM. It also inhibits the phosphorylation of AKT and ERK while upregulating the expression of TRAIL-R1/D5. UNC10245380 specifically kills cancer cells that are dependent on CIB1, demonstrating its potential value in the development of CIB1 probes and cancer research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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