8-Br-7-CH-ADPR
Product Specifications
CAS Number
1011457-95-6
Bioactivity
8-Br-7-CH-ADPR (8-Bromo-7-deazaadenosine-5-O-diphosphoribose) serves as a specific antagonist of TRPM2, functioning by binding to the NUDT9 homology domain within the TRPM2 channel, inhibiting its activation, and subsequently regulating the influx of cations through the cell membrane channel. This compound is utilized in research to explore the role of TRPM2 in processes such as cell death, neurodegenerative diseases, myocardial infarction, and diabetes.
Smiles
BrC=1N(C=2C(C1)=C(N)N=CN2)[C@@H]3O[C@H](COP(OP(OC[C@H]([C@H]([C@H](C=O)O)O)O)(=O)O)(=O)O)[C@@H](O)[C@H]3O
Molecular Formula
C16H23BrN4O14P2
Molecular Weight
637.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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