PPADS
Product Specifications
CAS Number
149017-66-3
Bioactivity
PPADS is a P2 receptor antagonist with IC50 values of 68 nM (P2X1) and 214 nM (P2X3) . This compound functions as an ATP (nucleotide) analog, competing for binding sites on the P2 receptors with ATP. Additionally, PPADS acts as a reversible competitive antagonist of the NAADP receptor. It is capable of reversing hyperalgesia, and it diminishes the enhanced NO/NOS signaling and IL-1? production in both peripheral and central steps of the nervous system.
Smiles
O=CC1=C(O)C(=NC(N=NC2=CC=C(C=C2S(=O)(=O)O)S(=O)(=O)O)=C1COP(=O)(O)O)C
Molecular Formula
C14H14N3O12PS2
Molecular Weight
511.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/235808112831889455/T89112
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
abx069573-01 10 µg
Human Tumor Necrosis Factor Ligand Superfamily Member 10 (TNFSF10) Protein
Ask
View Details 
abx069573-02 50 µg
Human Tumor Necrosis Factor Ligand Superfamily Member 10 (TNFSF10) Protein
Ask
View Details 
abx069573-03 100 µg
Human Tumor Necrosis Factor Ligand Superfamily Member 10 (TNFSF10) Protein
Ask
View Details abx069573-04 200 µg
Human Tumor Necrosis Factor Ligand Superfamily Member 10 (TNFSF10) Protein
Ask
View Details abx069573-05 500 µg
Human Tumor Necrosis Factor Ligand Superfamily Member 10 (TNFSF10) Protein
Ask
View Details MR202125L4V 200 µL
Gm5797 (NM_001025085) Mouse Tagged ORF Clone Lentiviral Particle
Ask
View Details