PI3K/Akt/mTOR-IN-5
Product Specifications
Target
Apoptosis, Akt, mTOR, STAT, PI3K
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Stem Cells, JAK/STAT signaling
Bioactivity
PI3K/Akt/mTOR-IN-5 (compound D3), a derivative of Pseudolaric Acid B, exhibits antitumor activity. This compound inhibits excessive proliferation of tumor cells through the PI3K/AKT/mTOR and STAT3/GPX4 pathways. Additionally, PI3K/Akt/mTOR-IN-5 effectively suppresses the EDU positive rate, reduces colony formation, and induces apoptosis (apoptosis) by arresting HCT-116 cells in the S and G2/M phases.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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