What is the catalog number for ZJCK-6-46?

The catalog number for ZJCK-6-46 is T89097.

What sizes are available for ZJCK-6-46?

ZJCK-6-46 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does ZJCK-6-46 come in?

ZJCK-6-46 is available in 2 different pack sizes.

Is ZJCK-6-46 in stock?

ZJCK-6-46 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ZJCK-6-46?

ZJCK-6-46 is manufactured by Molfinity.

What is the estimated delivery time for ZJCK-6-46?

Estimated delivery time for ZJCK-6-46 is approximately 10 business day(s), depending on your location.

ZJCK-6-46

Product Specifications

Target

DYRK

Related Pathways

Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint

Bioactivity

ZJCK-6-46 (32) is a potential orally active DYRK1A inhibitor (IC50= 0.68 nM) with favorable CNC permeability. It downregulates tau phosphorylation and improves cognitive impairments by significantly reducing the expression of phosphorylated tau proteins and neuronal loss.