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EPZ-4777

Product Specifications

CAS Number

1381761-52-9

Bioactivity

EPZ-4777 acts as a selective DOT1L inhibitor, effectively blocking the expression of leukemia-inducing genes by inhibiting methylation of H3K79 in cancer cells, and selectively targets and eradicates cells carrying translocations of this gene. It is utilized in tumor research.

Smiles

O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CN(CCCNC(NC4=CC=C(C(C)(C)C)C=C4)=O)C(C)C)[C@H]1O

Molecular Formula

C27H40N8O4

Molecular Weight

540.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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