EPZ-4777
Product Specifications
CAS Number
1381761-52-9
Bioactivity
EPZ-4777 acts as a selective DOT1L inhibitor, effectively blocking the expression of leukemia-inducing genes by inhibiting methylation of H3K79 in cancer cells, and selectively targets and eradicates cells carrying translocations of this gene. It is utilized in tumor research.
Smiles
O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CN(CCCNC(NC4=CC=C(C(C)(C)C)C=C4)=O)C(C)C)[C@H]1O
Molecular Formula
C27H40N8O4
Molecular Weight
540.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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TFDP1 (Transcription Factor Dp-1, DRTF1-polypeptide 1, DRTF1, E2F Dimerization Partner 1, DP1)
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