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HDAC6-IN-48

Product Specifications

Target

Apoptosis, HDAC

Related Pathways

Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

HDAC6-IN-48 (compound 5i) is a potent and selective inhibitor of HDAC6, exhibiting IC50 values of 5.16, 396.72, and 638.08 nM against HDAC6, HDAC3, and HDAC1, respectively. This compound induces cell apoptosis and arrests the cell cycle at the G0/G1 phase. Furthermore, HDAC6-IN-48 enhances the expression of acetylated α-tubulin.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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