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SRI-29574

Product Specifications

CAS Number

1928712-46-2

Bioactivity

SRI-29574 acts as an allosteric modulator of the dopamine transporter (DAT), partially inhibiting its uptake (IC50=2.3 nM) while also moderately inhibiting the uptake of serotonin transporter (SERT) and norepinephrine transporter (NET) . This compound serves as a valuable probe for researching the function and regulatory mechanisms of DAT.

Smiles

N=1C=CN2C=C(C=CC12)C3=NC=4C=CC=CC4C(=N3)NCC(C=5C=CC=CC5)C=6C=CC=CC6

Molecular Formula

C29H23N5

Molecular Weight

441.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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