KRAS inhibitor-25
Product Specifications
CAS Number
3030577-05-7
Target
Kras|||Ras
Related Pathways
MAPK
Bioactivity
KRAS inhibitor-25 (compound 151a), a pyrido[2,3-d]pyrimidine derivative, effectively inhibits KRas G12V, KRas WT, and KRas G12R with IC50 values all below 100 nM.
Smiles
C(OC1=NC2=C3C(=N1)C(F)=C(N=C3)C=4C(=C(Cl)C=C(O)C4)CCCCCCC5(O)CN2CCC5)[C@@]67N(C[C@H](F)C6)CCC7
Molecular Formula
C32H38ClF2N5O3
Molecular Weight
614.13
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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