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ZW-1226

Product Specifications

CAS Number

2351940-23-1

Bioactivity

ZW-1226 is a selective MRP1 inhibitor that reduces the uptake activity of MRP1 vesicles by 65% at a concentration of 5 μM. It inhibits MRP1 in a GSH-dependent manner and exhibits considerable selectivity towards MRP1 over other primary ABC transport proteins (including P-gp, BCRP, MRP2, and MRP3) .

Smiles

N#CC=1C=CC=2C=C3C(=O)NC(=O)N=C3N(C4=CC=C(OCC=5C=CC=CC5)C=C4)C2C1

Molecular Formula

C25H16N4O3

Molecular Weight

420.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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