ZW-1226
Product Specifications
CAS Number
2351940-23-1
Bioactivity
ZW-1226 is a selective MRP1 inhibitor that reduces the uptake activity of MRP1 vesicles by 65% at a concentration of 5 ?M. It inhibits MRP1 in a GSH-dependent manner and exhibits considerable selectivity towards MRP1 over other primary ABC transport proteins (including P-gp, BCRP, MRP2, and MRP3) .
Smiles
N#CC=1C=CC=2C=C3C(=O)NC(=O)N=C3N(C4=CC=C(OCC=5C=CC=CC5)C=C4)C2C1
Molecular Formula
C25H16N4O3
Molecular Weight
420.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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