What is the catalog number for RPS6-IN-1?

The catalog number for RPS6-IN-1 is T88975.

What sizes are available for RPS6-IN-1?

RPS6-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does RPS6-IN-1 come in?

RPS6-IN-1 is available in 2 different pack sizes.

Is RPS6-IN-1 in stock?

RPS6-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RPS6-IN-1?

RPS6-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for RPS6-IN-1?

Estimated delivery time for RPS6-IN-1 is approximately 10 business day(s), depending on your location.

RPS6-IN-1

Product Specifications

Target

Bcl-2 Family, Caspase, PARP, Apoptosis, Autophagy, MDM-2/p53

Related Pathways

DNA Damage/DNA Repair, Proteases/Proteasome, Autophagy, Apoptosis, Chromatin/Epigenetic

Bioactivity

RPS6-IN-1 (Compound 22o) inhibits cell migration and induces apoptosis (increasing the expression of Bax, p53, cleaved-caspase 3, and cleaved-PARP) . It reduces mitochondrial membrane potential and activates autophagy (Autophagy) through the PI3K-Akt-mTOR signaling pathway, damaging mitochondria and lysosomes within the cell and causing endoplasmic reticulum stress. RPS6-IN-1 also inhibits the phosphorylation of RPS6. Notably, RPS6-IN-1 is a low systemic toxicity anticancer agent.