PROTAC GSPT1 degrader-2
Product Specifications
CAS Number
3024909-61-0
Bioactivity
PROTACGSPT1 degrader-2 (compound A) acts as a molecular glue for GSPT1, achieving degradation efficiencies exceeding 95%. Meanwhile, GSPT1 degrader-8 exhibits inhibitory effects on HL-60 cells, demonstrating an IC50 of 10 nM.
Smiles
O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)N4CCC(CN5C(=O)N(C=6C=CC=C(C6)C=7C=NC=8NC=C(C8C7Cl)CC)CCC5)CC4)CC1
Molecular Formula
C38H38ClN7O5
Molecular Weight
708.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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