HDHODH-IN-15
Product Specifications
Target
Ferroptosis, Dehydrogenase
Related Pathways
Metabolism, Apoptosis
Bioactivity
HDHODH-IN-15 (Compound H19) acts as an inhibitor of human dihydroorotate dehydrogenase (hDHODH), demonstrating an IC50 of 0.21 μM. It exhibits cytotoxic effects in cancer cells such as NCI-H226, HCT-116, and MDA-MB-231, with IC50 values ranging from 0.95 to 2.81 μM. Furthermore, hDHODH-IN-15 induces ferroptosis in HCT-116 cells and shows antitumor activity.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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