What is the catalog number for LMP7/LMP2-IN-1?

The catalog number for LMP7/LMP2-IN-1 is T88971.

What sizes are available for LMP7/LMP2-IN-1?

LMP7/LMP2-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does LMP7/LMP2-IN-1 come in?

LMP7/LMP2-IN-1 is available in 2 different pack sizes.

Is LMP7/LMP2-IN-1 in stock?

LMP7/LMP2-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures LMP7/LMP2-IN-1?

LMP7/LMP2-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for LMP7/LMP2-IN-1?

Estimated delivery time for LMP7/LMP2-IN-1 is approximately 10 business day(s), depending on your location.

LMP7/LMP2-IN-1

Product Specifications

CAS Number

3053755-09-9

Target

Proteasome

Related Pathways

Proteases/Proteasome, Ubiquitination

Bioactivity

LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.