DL-threo-PPMP
Product Specifications
CAS Number
149022-18-4
Bioactivity
DL-threo-PPMP is an inhibitor of sphingosine synthetase (sphingosine synthetase) in Plasmodium falciparum. It inhibits the enzymes activity by binding to it, mimicking the substrate of sphingosine. This inhibition results in a rapid decline in the activity of sensitive sphingosine synthetase, selectively disrupting the interconnected tubular network in the cytoplasm of the host cell at the TVM. This action also blocks the proliferation of the Plasmodium falciparum. DL-threo-PPMP is valuable in studies of Plasmodium falciparum biology and the development of new anti-malarial strategies.
Smiles
[C@H]([C@H](O)C1=CC=CC=C1)(CN2CCOCC2)NC(CCCCCCCCCCCCCCC)=O
Molecular Formula
C29H50N2O3
Molecular Weight
474.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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