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DOTA.SA.FAPi TFA

Product Specifications

Target

Prolyl Endopeptidase (PREP)

Related Pathways

Metabolism, Proteases/Proteasome

Bioactivity

DOTA.SA.FAPi TFA is a bifunctional chelator composed of squaric acid (squaric acid) and UAMC1110, integrating the properties of DATA5m and DOTA. It exhibits inhibitory activity against fibroblast activation protein (FAP) with an IC50 of 0.9 nM and targets the prolyl endopeptidase (PREP) with an IC50 of 5.4 μM. After labeling with 68Ga, DOTA.SA.FAPi TFA serves as a PET tracer for cancer research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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