JMV6944
Product Specifications
CAS Number
2871774-93-3
Bioactivity
JMV6944 is a PXR agonist that competitively inhibits the binding of ligands to the ligand-binding domain (LBD) of human PXR, with an IC50 value of 680 nM. Additionally, JMV6944 induces the expression of CYP3A4 mRNA in cultures of freshly isolated primary human hepatocytes.
Smiles
O=S(=O)(NC=1C=CC2=C(N=C(N2CC=3C=CC=CC3)CCCCCCCN)C1)C=4C(=CC(=CC4C)C)C
Molecular Formula
C30H38N4O2S
Molecular Weight
518.71
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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