SMARCA2-IN-7
Product Specifications
CAS Number
2270879-43-9
Bioactivity
SMARCA2-IN-7 (compound 12) acts as a dual inhibitor for both BRM and BRG1 with IC50 values less than 0.005, exhibiting antitumor proliferation effects. It inhibits tumor proliferation in SKMEL5 cells lacking BRG1 with an AAC50 of 13 nM. Additionally, in H1299 cells, it suppresses cell proliferation activity of KRT880 with an AAC50 of 42 nM.
Smiles
O=C(NC=1SN=C(C1)C(F)F)NC2=CC(Cl)=NC=C2CO
Molecular Formula
C11H9ClF2N4O2S
Molecular Weight
334.73
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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