Casdatifan
Product Specifications
CAS Number
2709069-30-5
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Metabolism|||Chromatin/Epigenetic
Bioactivity
Casdaitifan (AB521) is an orally active hypoxia inducible factor 2 alpha (HIF-2 alpha) inhibitor. Casdaitifan exhibits significant anti-tumor effects in the clear cell renal cell carcinoma (ccRCC) model.
Smiles
C(#N)C1=C2[C@H](C[C@H](F)[C@H](F)C2=CC(F)=C1)C3=C4C(=C(S(C)(=O)=O)C=C3)[C@H](O)[C@H](F)C4
Molecular Formula
C21H17F4NO3S
Molecular Weight
439.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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