Molidustat sodium
Product Specifications
CAS Number
1375799-59-9
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic|||Metabolism
Bioactivity
Molidustat sodium (5 ?M; 20 min) is sufficient to induce detectable levels of HIF-1? in HeLa cells. In a cellular reporter assay, the compound stimulates the expression of the luciferase reporter gene under the control of a hypoxia-responsive element promoter, with an average (± SD) EC50 of 8.4 ?M (n=4) .
Smiles
[Na].OC1=C(C=NN1C2=NC=NC(=C2)N3CCOCC3)N4N=NC=C4
Molecular Formula
C13H13N8NaO2
Molecular Weight
336.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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