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2'-O-MB-cGMP sodium

Product Specifications

CAS Number

58329-72-9

Target

PDE

Related Pathways

Metabolism

Bioactivity

2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium functions as an inhibitor of cyclic GMP-specific phosphodiesterases (cyclic GMP-specific phosphodiesterase), exhibiting an IC50 value of 35 μM. This compound effectively inhibits the hydrolysis of phosphodiesterases that use cAMP or cGMP as substrates in a Ca2+-dependent manner.

Smiles

O(C(CCC)=O)[C@H]1[C@@H](O[C@]2([C@]1(OP(=O)(O)OC2)[H])[H])N3C4=C(N=C3)C(=O)N=C(N)N4.[Na]

Molecular Formula

C14H17N5NaO8P

Molecular Weight

437.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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