PARP-1-IN-23
Product Specifications
CAS Number
2976497-48-8
Target
PARP
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
PARP-1-IN-23 (Compound I16) is an orally bioavailable, selective inhibitor of PARP-1, exhibiting an IC50 of 12.38 nM. This compound demonstrates efficacy in inhibiting tumor growth in vivo.
Smiles
O=C(N)C=1C=CC=C2N=C(NC21)C=3C=C(Br)C(OS(=O)(=O)C=4C=CC=CC4C)=C(OC)C3
Molecular Formula
C22H18BrN3O5S
Molecular Weight
516.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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