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PARP-1-IN-23

Product Specifications

CAS Number

2976497-48-8

Target

PARP

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

PARP-1-IN-23 (Compound I16) is an orally bioavailable, selective inhibitor of PARP-1, exhibiting an IC50 of 12.38 nM. This compound demonstrates efficacy in inhibiting tumor growth in vivo.

Smiles

O=C(N)C=1C=CC=C2N=C(NC21)C=3C=C(Br)C(OS(=O)(=O)C=4C=CC=CC4C)=C(OC)C3

Molecular Formula

C22H18BrN3O5S

Molecular Weight

516.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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