HbF inducer 2

Product Specifications

CAS Number

2654011-51-3

Target

Molecular Glues

Related Pathways

PROTAC

Purity

0.999

Bioactivity

HbF inducer 2 (Compound dWIZ-2) is an orally bioavailable PROTAC molecular glue that degrades the WIZ transcription factor (DC50 = 13 nM) and induces foetal haemoglobin (HbF) expression (EC50 = 100 nM) .

Smiles

O=C1N(CC=2C1=CC=C(OC[C@@H]3N(CC)CCCC3)C2)C4C(=O)NC(=O)CC4

Molecular Formula

C21H27N3O4

Molecular Weight

385.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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