HbF inducer 2
Product Specifications
CAS Number
2654011-51-3
Target
Molecular Glues
Related Pathways
PROTAC
Purity
0.999
Bioactivity
HbF inducer 2 (Compound dWIZ-2) is an orally bioavailable PROTAC molecular glue that degrades the WIZ transcription factor (DC50 = 13 nM) and induces foetal haemoglobin (HbF) expression (EC50 = 100 nM) .
Smiles
O=C1N(CC=2C1=CC=C(OC[C@@H]3N(CC)CCCC3)C2)C4C(=O)NC(=O)CC4
Molecular Formula
C21H27N3O4
Molecular Weight
385.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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