8-pCPT-cGMP-AM
Product Specifications
CAS Number
272445-72-4
Target
PKA
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
8-pCPT-cGMP-AM (8- (4-Chlorophenylthio) -cGMP-AM) is a highly membrane-permeable prodrug of the PKG agonist 8-pCPT-cGMP, designed to enhance membrane permeability of cGMP. It is converted into its active form within the cell via esterase hydrolysis, thus activating PKG. This compound is utilized to investigate the role of cGMP signaling in neural plasticity and memory formation.
Smiles
S(C=1N(C2=C(N1)C(=O)N=C(N)N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(OCOC(C)=O)(=O)O4)[H])[H])C5=CC=C(Cl)C=C5
Molecular Formula
C19H19ClN5O9PS
Molecular Weight
559.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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