JANEX-1 hydrochloride
Product Specifications
CAS Number
188829-39-2
Target
JAK
Related Pathways
Chromatin/Epigenetic|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Stem Cells
Bioactivity
JANEX-1 (WHI-P131) hydrochloride is an effective and specific JAK3 inhibitor with a Ki of 2.3 ?M and an IC50 of 78 ?M. It does not inhibit JAK1 and JAK2.
Smiles
Cl.OC1=CC=C(C=C1)NC=2N=CN=C3C=C(OC)C(OC)=CC32
Molecular Formula
C16H16ClN3O3
Molecular Weight
333.77
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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