Fumagilin-105
Product Specifications
CAS Number
2410081-58-0
Target
Autophagy|||Estrogen Receptor/ERR|||AUTACs|||p62
Related Pathways
Autophagy|||Endocrinology/Hormones|||PROTAC
Bioactivity
Fumagilin-105, an autophagy-targeting chimera (AUTOTAC), induces self-oligomerization of p62 and exhibits a DC50 of 0.7 ?M against MetAP2 in HEK293 cells.
Smiles
C[C@@]1([C@@]2([C@@]3(CO3)CC[C@@H](OC(/C=C/C=C/C=C/C=C/C(NCCOCCOCCNCC4=CC(OCC5=CC=CC=C5)=CC=C4)=O)=O)[C@H]2OC)[H])[C@@H](CC=C(C)C)O1
Molecular Formula
C46H60N2O9
Molecular Weight
784.98
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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