KRAS G12D inhibitor 24
Product Specifications
CAS Number
3033701-29-7
Target
Ras, Kras
Related Pathways
GPCR/G Protein, MAPK
Bioactivity
KRAS G12D Inhibitor 24 (compound 103) is an effective inhibitor of KRAS G12D with an IC50 of 0.004 μM. It exhibits oral bioactivity.
Smiles
C(#C)C=1C=2C(=CC(O)=CC2C=CC1F)C3=C(F)C4=C(C=N3)C(=NC(OC[C@@]5(C)\C(=C\F)\CCN(C)C5)=N4)N6CC7NC(C6)CC7
Molecular Formula
C34H33F3N6O2
Molecular Weight
614.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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