Monoamine Oxidase B inhibitor 5
Product Specifications
CAS Number
2969160-15-2
Target
Monoamine Oxidase
Related Pathways
Neuroscience
Bioactivity
Monoamine OxidaseB inhibitor 5 (Compound 16d) is a reversible and selective inhibitor of monoamine oxidase B (hMAO-B), with an IC50 value of 67.3 nM and a Ki of 82.5 nM. It exhibits favorable pharmacokinetic properties and low toxicity in rat models. Additionally, this compound alleviates motor impairments in a Parkinson's mouse model induced by MPTP, and it is characterized by its ability to penetrate the blood-brain barrier (BBB) .
Smiles
O=C(N)CC1=NC=2C=CC(OCC3=CC=C(F)C=C3)=CC2N1
Molecular Formula
C16H14FN3O2
Molecular Weight
299.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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