WIZ degrader 1
Product Specifications
CAS Number
2839552-68-8
Target
Histone Methyltransferase|||Others
Related Pathways
Others|||Chromatin/Epigenetic
Bioactivity
WIZ degrader 1 (Compound 141) is a degrader of the wide-interval zinc-finger motif (WIZ) with an AC50 of 2 nM. It can induce the expression of fetal hemoglobin (HbF), exhibiting an EC50 value of 6 mM. WIZ degrader 1 is used in the research of genetic blood disorders.
Smiles
C(C1=CC2=C(C=NN2C=C1)N3C(=O)NC(=O)CC3)[C@H]4C[C@H](C)N(CC5CCC(F)(F)CC5)CC4
Molecular Formula
C25H33F2N5O2
Molecular Weight
473.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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