What is the catalog number for Antitumor agent-171?

The catalog number for Antitumor agent-171 is T88683.

What sizes are available for Antitumor agent-171?

Antitumor agent-171 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does Antitumor agent-171 come in?

Antitumor agent-171 is available in 3 different pack sizes.

Is Antitumor agent-171 in stock?

Antitumor agent-171 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Antitumor agent-171?

Antitumor agent-171 is manufactured by Molfinity.

What is the estimated delivery time for Antitumor agent-171?

Estimated delivery time for Antitumor agent-171 is approximately 10 business day(s), depending on your location.

Antitumor agent-171

Product Specifications

CAS Number

3003004-76-7

Target

Wnt/beta-catenin

Related Pathways

Stem Cells, Cytoskeletal Signaling

Bioactivity

Antitumor agent-171 (Compound 35) acts as an inhibitor of the β-catenin/BCL9 interaction, with an IC50 of 1.61 μM. It suppresses the expression of the axin2 gene, demonstrating an IC50 value of 0.84 μM, and exhibits high affinity for β-catenin with a Kd of 0.63 μM. Additionally, Antitumor agent-171 inhibits the viability of HCT116 cells with an IC50 of 4.39 μM. It activates T cells, enhances antigen presentation, and shows antitumor activity and favorable pharmacokinetic properties in murine models.