P2Y14R antagonist 1
Product Specifications
CAS Number
2728291-29-8
Target
NOD-like Receptor (NLR) |||P2Y Receptor
Related Pathways
Neuroscience|||GPCR/G Protein|||Immunology/Inflammation
Purity
0.9888
Bioactivity
P2Y14R antagonist 1 (compound I-17) is a selective and potent P2Y14R antagonist (IC50=0.6 nM) with oral activity and good bioavailability that inhibits monosodium urate-induced inflammatory response in acute gouty arthritis by reducing inflammatory factor release via the NLRP3/GSDMD signaling pathway and cellular pyroptosis.
Smiles
O=C(NC=1C=CC=2N=CNC2C1)COC3=CC=C(Br)C=C3
Molecular Formula
C15H12BrN3O2
Molecular Weight
346.18
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal Proapoptotic Caspase Adaptor Protein Antibody [PerCP]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-97099PCP 0.1 mL
Rabbit Polyclonal Proapoptotic Caspase Adaptor Protein Antibody [PerCP]
Ask
View Details 
MBS055210-01 48 Well
Horse Membrane Spanning 4 Domains Subfamily A, Member 1 ELISA Kit
Ask
View Details 
MBS055210-02 96 Well
Horse Membrane Spanning 4 Domains Subfamily A, Member 1 ELISA Kit
Ask
View Details MBS055210-03 5x 96 Well
Horse Membrane Spanning 4 Domains Subfamily A, Member 1 ELISA Kit
Ask
View Details MBS055210-04 10x 96 Well
Horse Membrane Spanning 4 Domains Subfamily A, Member 1 ELISA Kit
Ask
View Details