Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BPR5K230

Product Specifications

CAS Number

3029897-97-7

Target

TAM Receptor

Related Pathways

Tyrosine Kinase/Adaptors

Bioactivity

BPR5K230 is a dual inhibitor of the receptor tyrosine kinases MER and AXL, exhibiting IC50 values of 4.1 nM and 9.2 nM, respectively. It inhibits the proliferation of Ba/F3-MER cells with an IC50 of 5 nM. BPR5K230 demonstrates favorable pharmacokinetics in mice and displays anti-inflammatory and antitumor effects in mouse models against 4T1, MDA-MB-231, MC38, and Hepa1-6.

Smiles

O=C(NC1=CC=C(OC=2N=CN=C3OC(C=4C=NN(C4)C)=C(C5=CC=CC(=C5)CN(C)C)C23)C=C1)C6=CC=CN(C6=O)C7=CC=C(F)C=C7

Molecular Formula

C37H30FN7O4

Molecular Weight

655.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Polyclonal PTPN3 Antibody [Alexa Fluor 647]

NBP3-18412AF647 0.1 mL

Rabbit Polyclonal PTPN3 Antibody [Alexa Fluor 647]

Sign In for Pricing

RCV1 (Recoverin, RCV1) (FITC)

MBS6176443-01 0.1 mL

RCV1 (Recoverin, RCV1) (FITC)

Sign In for Pricing

RCV1 (Recoverin, RCV1) (FITC)

MBS6176443-02 5x 0.1 mL

RCV1 (Recoverin, RCV1) (FITC)

Sign In for Pricing

4,4'-Butylidenebis (6-tert-butyl-3-methylphenol)

JH509495 1 Each

4,4'-Butylidenebis (6-tert-butyl-3-methylphenol)

Sign In for Pricing

TMEM22 Protein Lysate (Rat) with C-HA Tag

47008036 100 µg

TMEM22 Protein Lysate (Rat) with C-HA Tag

Sign In for Pricing

RO4929097

MBS8506379-01 5 mg

RO4929097

Sign In for Pricing