Antitumor agent-172
Product Specifications
CAS Number
3027905-74-1
Target
Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling, Stem Cells
Bioactivity
Antitumor agent-172 (Compound 28) acts as an inhibitor of the β-catenin/BCL9 interaction, featuring an IC50 of 3.92 μM. This compound exhibits high affinity for β-catenin, with a Kd of 82 nM. Furthermore, Antitumor agent-172 activates T cells, enhances antigen presentation, and demonstrates antitumor activity along with favorable pharmacokinetic properties in murine models.
Smiles
N(CC1=CC=C(C=C1)C=2C=NNC2)(C(N[C@H]3CN(CCC3)C4=CC(OC(C(NCC(=O)N5C(CCN)CCC5)=O)(C)C)=CC=C4)=O)C6CC6
Molecular Formula
C37H50N8O4
Molecular Weight
670.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2042434-01 0.1 mL
Cy3-Linked Polyclonal Antibody to Prohibitin (PHB)
Sign In for Pricing
View Details MBS2042434-02 0.2 mL
Cy3-Linked Polyclonal Antibody to Prohibitin (PHB)
Sign In for Pricing
View Details MBS2042434-03 0.5 mL
Cy3-Linked Polyclonal Antibody to Prohibitin (PHB)
Sign In for Pricing
View Details MBS2042434-04 1 mL
Cy3-Linked Polyclonal Antibody to Prohibitin (PHB)
Sign In for Pricing
View Details