CDD-1653
Product Specifications
CAS Number
3034216-44-6
Target
TGF-beta/Smad
Related Pathways
Stem Cells
Bioactivity
CDD-1653 is a potent BMPR2 selective inhibitor with an IC50 of 2.8 nM. It acts by inhibiting the binding of ATP to the kinase domain of BMPR2, thereby affecting the phosphorylation of the transcription factors SMAD1/5/8, which play a crucial role in the BMP signaling pathway. CDD-1653 is utilized in research related to diseases associated with the BMP signaling pathway.
Smiles
O=C1N(C=2C=CC=CC2)CCN(C3=NC(=NC=C3OC)NC4=CC=CC(=C4)S(=O)(=O)N)C1
Molecular Formula
C21H22N6O4S
Molecular Weight
454.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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