PCS1055
Product Specifications
CAS Number
357173-55-8
Target
AChR, Cholinesterase (ChE)
Related Pathways
Neuroscience
Bioactivity
PCS1055 is a selective and competitive antagonist of the muscarinic M4 receptor (muscarinic M4 receptor), with an IC50 of 18.1 nM and a Kd of 5.72 nM. It inhibits the binding of the radioligand [3H]-NMS to the M4 receptor, with a Ki of 6.5 nM. Additionally, PCS1055 acts as an AChE inhibitor, exhibiting IC50 values of 22 nM for electric eel AChE and 120 nM for human AChE.
Smiles
N1=NC=2C3=CC=CC=C3CCCC2C=C1NCCC4CCN(CC=5C=CC=CC5)CC4
Molecular Formula
C27H32N4
Molecular Weight
412.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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