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MRS5663

Product Specifications

CAS Number

1377272-66-6

Target

Adenosine Receptor

Related Pathways

GPCR/G Protein, Neuroscience

Bioactivity

MRS5663 (Compound 3a), an A3AR agonist, exhibits an EC50 value of 5.62 nM in β-arrestin2 recruitment assays. This compound demonstrates cytoprotective effects in skeletal muscle ischemia-reperfusion injury/claudication models.

Smiles

C(NC)(=O)[C@]12[C@](C1)([C@H]([C@H](O)[C@@H]2O)N3C=4C(N=C3)=C(NC)N=C(C#CC5=C(Cl)C=CC=C5)N4)[H]

Molecular Formula

C22H21ClN6O3

Molecular Weight

452.89

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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