MRS5663
Product Specifications
CAS Number
1377272-66-6
Target
Adenosine Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
MRS5663 (Compound 3a), an A3AR agonist, exhibits an EC50 value of 5.62 nM in β-arrestin2 recruitment assays. This compound demonstrates cytoprotective effects in skeletal muscle ischemia-reperfusion injury/claudication models.
Smiles
C(NC)(=O)[C@]12[C@](C1)([C@H]([C@H](O)[C@@H]2O)N3C=4C(N=C3)=C(NC)N=C(C#CC5=C(Cl)C=CC=C5)N4)[H]
Molecular Formula
C22H21ClN6O3
Molecular Weight
452.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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